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WAY-208466 dihydrochloride,≥98% (HPLC)

别名:WAY208466二盐酸盐;WAY208466 dihydrochloride, WAY 208466 dihydrochloride, 3-[(3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine hydrochloride (1:2)

Empirical Formula (Hill Notation): C17H18FN3O2S · 2HCl CAS号: 1207064-61-6 分子量: 420.33 MDL编号: MFCD28384460 PubChem化学物质编号: 329823827 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0305
CAS号: 1207064-61-6
MDL号: MFCD28384460
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€228.53

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

WAY-208466 is a high affinity (Ki = 4.8 nM) 5-HT6 receptor agonist. In HeLa cells expressing cloned human 5-HT6, the compound induced cAMP production (EC50 = 7.3 nM; Emax = 100%). WAY-208466 increases cortical GABA levels and exhibits anxiolytic activity in rat studies.
 
WAY-208466 是一种高亲和力 (Ki = 4.8 nM) 5-HT6 受体激动剂。 在表达克隆人 5-HT6 的 HeLa 细胞中,该化合物诱导了 cAMP 的产生(EC50 = 7.3 nM;Emax = 100%)。 WAY-208466 增加皮质 GABA 水平并在大鼠研究中表现出抗焦虑活性。
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

H2O: 5 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

SMILES string

CN(C)CCN1C=C(S(C2=CC=CC(F)=C2)(=O)=O)C3=CC=CN=C31

InChI

1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3

InChI key

SFSFIDVAEMDPIP-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16