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信号通路, 信号转导, Cell Signaling

20,000多种特异性抑制剂、激动剂作用于表观遗传学、PI3K/Akt/mTOR、凋亡、MAPK、Wnt等20多个信号通路的375个靶点蛋白,覆盖癌症、神经科学、免疫学等热门疾病研究领域。BSZH北实纵横科学公司的50多种活性化合物库,包含10,000多种具有生物活性的小分子化合物,可用于高通量筛选 (HTS)和高内涵筛选 (HCS),是进行新药筛选和新适应症发现等研究的专业工具。

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花生四烯酸乙醇胺,Arachidonylethanolamide [AEA];≥97.0% (TLC), oil

A0580
别名:大麻素, 花生四烯酸 N-(羟乙基)酰胺, 苯酰胺 (20:4, n-6);AEA, Anandamide (20:4, n-6), Anandamide, Arachidonic acid N-(hydroxyethyl)amide

CAS号 94421-68-8 经验分子式(希尔表示法) C22H37NO2 分子量 347.53 MDL number MFCD00153766 PubChem Substance ID 24890438 NACRES NA.25
¥1,337.52

DAPT;N-[N-(3,5-二氟苯乙酰)-L-丙氨酰]-S-苯甘氨酸叔丁酯 [GSI-IX, LY-374973];≥98% (HPLC)

D5942
别名:DAPT, 一种γ-secretase 抑制剂;(3,5-二氟苯乙酰基)-L-丙氨酰基-L-2-苯基甘氨酸叔丁酯;N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester

CAS号 208255-80-5 经验分子式(希尔表示法) C23H26F2N2O4 分子量 432.46 MDL number MFCD04974585 PubChem Substance ID 24893987 NACRES NA.77
¥2,243.81

DAPT;N-[N-(3,5-二氟苯乙酰)-L-丙氨酰]-S-苯甘氨酸叔丁酯 [GSI-IX, LY-374973];Calbiochem®, ≥98% (HPLC)

565770
别名:DAPT, 一种γ-secretase 抑制剂;(3,5-二氟苯乙酰基)-L-丙氨酰基-L-2-苯基甘氨酸叔丁酯;N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester

CAS号 208255-80-5 经验分子式(希尔表示法) C23H26F2N2O4 分子量 432.46 MDL number MFCD04974585
¥1,576.97

地塞米松,Dexamethasone [DXMS];powder, BioReagent, suitable for cell culture, ≥97%

D4902
别名:德沙美松;21α-乙酰氧基-9α-氟-11β,17α-二羟基-16α-甲基孕甾-1,4-二烯-3,20-二酮;9α-氟-16α-甲基氢化泼尼松;9-氟-11,17,21-三羟基-16-甲基(11b,16a)-孕甾-1,4-二烯-3,20-二酮;(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

CAS号 50-02-2 经验分子式(希尔表示法) C22H29FO5 分子量 392.46 Beilstein/REAXYS Number 2066651 EINECS 编号 200-003-9 MDL number MFCD00064136 PubChem Substance ID 24893906 NACRES NA.75
¥697.30

索拉非尼 [Raf抑制剂, 索拉菲尼],Sorafenib;≥98% (HPLC)

SML2653
别名:4-[4-[[[[4-氯-3-(三氟甲基)苯基]氨基]羰基]氨基]苯氧基]-N-甲基-2-吡啶甲酰胺;4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide;BAY 43-9006;BAY43-9006;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea

CAS号 284461-73-0 经验分子式(希尔表示法) C21H16ClF3N4O3 分子量 464.82 MDL number MFCD06411450
¥995.00

人肿瘤坏死因子-α,Tumor Necrosis Factor-α human;TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture, ≥97% (SDS-PAGE)

T6674
别名::TNF-α;hTNF-α;TNFα;TNF-a;TNFa;重组人肿瘤坏死因子a在E. coli中表达

CAS号 94948-59-1 MDL number MFCD00148692 NACRES NA.77
¥4,418.77

人白细胞介素IL-1β,IL-1 beta human [IL1β];Animal-component free, recombinant, expressed in E. coli, ≥98%, HPLC, suitable for cell culture

SRP3083
别名:重组人白介素IL1β/IL1b;无动物成分重组人白细胞介素1β;内源性热原(EP);单核细胞因子(MCF);淋巴细胞激活因子(LAF);白细胞内源介质(LEM), Catabolin;Endogenous Pyrogen (EP);Leukocyte Endogenous Mediator (LEM);Lymphocyte-activating factor (LAF);Mononuclear Cell Factor (MCF)
¥4,379.78

重组人表皮细胞生长因子,Human Epidermal Growth Factor [EGF];recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97%

E9644
别名:重组人表皮生长因子;hEGF;人EGF;h-EGF;rh-EGF;Recombinant Human EGF;Epidermal Growth Factor human

CAS号 62253-63-8 MDL number MFCD00132565 NACRES NA.77
¥2,807.21

人白细胞介素 [重组人白介素IL2, TCGF],Interleukin-2 [IL-2 human];Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture

SRP3085
别名:人白细胞介素-2;人白介素-2;T细胞生长因子(TCGF);阿地白介素;Aldesleukin;T-cell growth factor (TCGF);Recombinant Human IL-2
¥4,379.78

L-α-磷脂酰肌醇4,5-二磷酸酯钠盐,L-α-Phosphatidylinositol 4,5-diphosphate sodium salt from bovine brain [PIP2]

P9763
别名: PIP2来源于牛大脑,1,2-二酰基-sn-甘油-3-磷酸基-(1-D-myo-肌醇 4,5-二磷酸酯) 钠盐, PIP2, 三磷酸肌醇磷脂 钠盐;1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol 4,5-bisphosphate) sodium salt, PIP2, Triphosphoinositide sodium salt
¥30,313.46

1,2-二油酰-锡-甘油基-3-磷酸胆碱,1,2-Dioleoyl-sn-glycero-3-phosphocholine;≥99% (TLC) [DOPC, PC]

P6354
别名:1,2-二(顺式-9-油酰基)-sn-甘油-3-磷酸胆碱, 1,2-二油酰基-3-sn-磷脂酰胆碱, L-β,γ-二油酰基-α-卵磷脂, 二油酰基-L-α-磷脂酰胆碱;1,2-Di(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dioleoyl, L-α-Phosphatidylcholine, dioleoyl, L-β,γ-Dioleoyl-α-lecithin, DOPC, PC

CAS号 4235-95-4 经验分子式(希尔表示法) C44H84NO8P 分子量 786.11 Beilstein/REAXYS Number 3898070 EINECS 编号 224-193-8 MDL number MFCD00135191 PubChem Substance ID 24898758 NACRES NA.25
¥545.26

佛司可林,Forskolin;from Coleus forskohlii, ≥98% [毛喉素, 考福新]

F6886
别名:7β-乙酰氧基-8,13--环氧-1α,6β,9α-三羟基labd-14-烯-11-酮;洋紫苏醇;福司柯林;7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Coleonol, Colforsin

CAS号 66575-29-9 经验分子式(希尔表示法) C22H34O7 分子量 410.50 Beilstein/REAXYS Number 1692716 EINECS 编号 266-410-9 MDL number MFCD00082317 PubChem Substance ID 24278035 NACRES NA.77
¥2,320.76