SGC-AAK1-1N is a structure analog of and the recommended negative control for SGC-AAK1-1
(AAK1 IC50 = 11 μM and 270 nM, respectively, by coupled enzyme assay; KD
= 8.8 μM/AAK1 & >10 μM/BIKE with SGC-AAK1-1N vs. KD
= 26 nM/AAK1 & 930 nM/BIKE with SGC-AAK1-1). For characterization details of the active probe, SGC-AAK1-1, please visit the SGC-AAK1-1 probe summary
on the Structural Genomics Consortium (SGC) website.
SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1, click here
To learn about other SGC chemical probes, visit sigma.com/sgc