SGC-AAK1-1N is a structure analog of and the recommended negative control for
SGC-AAK1-1 (AAK1 IC50 = 11 μM and 270 nM, respectively, by coupled enzyme assay; K
D = 8.8 μM/AAK1 & >10 μM/BIKE with SGC-AAK1-1N vs. K
D = 26 nM/AAK1 & 930 nM/BIKE with SGC-AAK1-1). For characterization details of the active probe, SGC-AAK1-1, please visit the
SGC-AAK1-1 probe summary on the Structural Genomics Consortium (SGC) website.
SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1,
click here.
To learn about other SGC chemical probes, visit
sigma.com/sgc