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PF-04880594,≥98% (HPLC)

别名:PF04880594;PF 04880594;3-[[4-[1-(2,2-Difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-propanenitrile

Empirical Formula (Hill Notation): C19H16F2N8 CAS号: 1111636-35-1 分子量: 394.38 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0294
CAS号: 1111636-35-1
MDL号: MFCD26142632
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$354.21

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-04880594 is a potent and selective RAF inhibitor that inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 potently inhibits tumor growth in BRAF-mutant melanoma xenograft models.
 
PF-04880594 是一种有效的选择性 RAF 抑制剂,可抑制野生型和突变型 BRAF 和 CRAF。 PF-04880594 在 BRAF 突变黑色素瘤异种移植模型中有效抑制肿瘤生长。
 

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

SMILES string

FC(F)CN(N=C1C2=CC(C=CN3)=C3N=C2)C=C1C4=NC(NCCC#N)=NC=C4

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16