5, 25 mg in glass bottle
KRN633 is a cell-permeable; reversible and ATP-competitive inhibitor of vascular endothelial growth factor receptor tyrosine kinase (VEGFR) with IC50 values of 170, 160, and 125 nM for VEGFR-1, -2, -3, respectively. Krn633 inhibits PDGFR-α and c-Kit only at higher concentrations (IC50 = 0.97 and 4.33 μM, respectively) and is inactive towards a panel of 17 other kinases (IC50 >/= 10 μM).
Features and Benefits
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|Quality Level ||100|
|assay ||≥98% (HPLC)|
|color ||white to beige|
|solubility ||DMSO: 3 mg/mL, clear (warmed)|
|storage temp. ||−20°C|
RIDADR NONH for all modes of transport