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烟酸 [维生素B3],Nicotinic acid;meets USP testing specifications, 99.0-101.0% dry basis

别名:3-吡啶甲酸;吡啶-3-羧酸;尼亚生;尼克酸;抗癞皮病因子;抗糙皮病因子;维生素 B3;尼古丁酸;维生素PP;3-Picolinic acid;Niacin;Pellagra preventive factor;Pyridine-3-carboxylic acid;Vitamin B3

CAS号 59-67-6 经验分子式(希尔表示法) C6H5NO2 分子量 123.11 Beilstein/REAXYS Number 109591 EINECS 编号 200-441-0 MDL number MFCD00006391 PubChem Substance ID 24897734 NACRES NA.21
货号(SKU): N5410
CAS号: 59-67-6
MDL号: MFCD00006391
增值税发票 √ 免费货运 [顺丰 联邦] √
¥3,747.75

产品描述

General description

Nicotinic acid, also referred to as niacin or as vitamin B3[1], is a water-soluble vitamin.[2] Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.[3]

Application

Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.[7]

Biochem/physiol Actions

Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia.[1] It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides.[3] Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease[3] Deficiency also impacts DNA repair[6] and also leads to skin and gastrointestinal disorder, pellagra.[5] Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.[4]

性质

Quality Level200
biological sourcesynthetic (organic)
Agency/Methodmeets USP testing specifications
assay99.0-101.0% dry basis
formpowder
colorwhite
mp236-239 °C (lit.)
Featured IndustryPharmaceutical (small molecule)
SMILES stringOC(=O)c1cccnc1
InChI1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI keyPVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544)
rat ... Chrnb2(54239)


安全信息

符号
GHS07  GHS07
信号词 Warning
危害声明 H319
警示性声明 P305 + P351 + P338
个人防护装备 dust mask type N95 (US)EyeshieldsGloves
危害码 (欧洲) Xi
风险声明 (欧洲) 36
安全声明 (欧洲) 26
RIDADR NONH for all modes of transport
WGK德国 WGK 1
RTECS QT0525000
闪点(华氏) 379.4 °F - closed cup
闪点(摄氏) 193 °C - closed cup
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
商品标签