烟酸 [维生素B3]，Nicotinic acid；meets USP testing specifications, 99.0-101.0% dry basis

General description

Nicotinic acid, also referred to as niacin or as vitamin B₃^[1], is a water-soluble vitamin.^[2] Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.^[3]

Application

Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.^[7]

Biochem/physiol Actions

Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia.^[1] It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides.^[3] Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease^[3] Deficiency also impacts DNA repair^[6] and also leads to skin and gastrointestinal disorder, pellagra.^[5] Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.^[4]

性质

安全信息

符号

  GHS07

信号词 Warning

危害声明 H319

警示性声明 P305 + P351 + P338

个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

危害码 (欧洲) Xi

风险声明 (欧洲) 36

安全声明 (欧洲) 26

RIDADR NONH for all modes of transport

WGK德国 WGK 1

RTECS QT0525000

闪点（华氏） 379.4 °F - closed cup

闪点（摄氏） 193 °C - closed cup