Catalogue Number | L469482 |
Chemical Name | Lopinavir-d8 |
Synonyms | (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide- d8; A 157378.0-d8; ABT 378-d8; Aluviran-d8; Koletra-d8; |
CAS Number | 1322625-54-6 |
Alternate CAS # | 192725-17-0-unlabelled |
Molecular Formula | C₃₇H₄₀D₈N₄O₅ |
Appearance | Off-White to Pale Beige Solid |
Melting Point | >96°C (dec.) |
Molecular Weight | 636.85 |
Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Category | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product. |
References | Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999) |