SGC-GAK-1N，≥98% (HPLC)

图片 SGC-GAK-1N，≥98% (HPLC)
别名：N-甲基-6-(三氟甲基)-N-(3,4,5-三甲氧基苯基)喹啉-4-胺，CA93 阴性对照，CA71，SGC-GAK-1 阴性对照；N-Methyl-6-(trifluoromethyl)-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine, CA93 Negative Control, CA71, SGC-GAK-1 Negative Control

Empirical Formula (Hill Notation): C20H19F3N2O3 分子量: 392.37 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML2203
CAS号: 2226517-74-2
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥1,524.91

说明

生化/生理作用

SGC-GAK-1N (CA71) is a structure analog of and the recommended negative control for the ATP-competitive cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 (CA93) (GAK KD = 1.9 nM/SGC-GAK-1 vs. 7.1 μM/SGC-GAK-1N by ligand competitive binding assay; GAK IC50 = 110 nM/SGC-GAK-1 vs. >50 μM/SGC-GAK-1N by cellular target engagement assay; Dengue viral entry and packaging IC50 = 920 nM/SGC-GAK-1 vs. >10 μM/SGC-GAK-1N). For characterization details of the active probe, SGC-GAK-1, please visit the SGC-GAK-1 probe summary on the Structural Genomics Consortium (SGC) website.

SGC-GAK-1, the active probe, is available from Sigma. To learn more about and purchase SGC-GAK-1, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
 

特点和优势

SGC-GAK-1N is a negative control for SGC-GAK-1, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC
 
 

属性

测定

≥98% (HPLC)

形式

powder

颜色

dark green to black

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES string

CN(C1=CC(OC)=C(OC)C(OC)=C1)C2=C3C(C=CC(C(F)(F)F)=C3)=NC=C2

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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