BI-9564，≥97% (HPLC)

图片 BI-9564，≥97% (HPLC)
别名：4-(4-二甲氨基甲基-2,5-二甲氧基苯基)-2-甲基-2H-[2,7]萘啶-1-酮；4-[4-[二甲基氨基甲基]-2,5-二甲氧基苯基]-2-甲基-2,7-萘啶-1-酮；4-(4-Dimethylaminomethyl-2,5-dimethoxy-phenyl)-2-methyl-2H-[2,7]naphthyridin-1-one, 4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1-one, GTPL8950

Empirical Formula (Hill Notation): C20H23N3O3 CAS号: 1883429-22-8 分子量: 353.41 PubChem化学物质编号: 329825994 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML1655
CAS号: 1883429-22-8
MDL号: MFCD30182324
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说明

生化/生理作用

BI-9564 decreases the development of tumors and enhances the survival rate in treated mice.[1] It can block BRD9 (bromodomain-containing protein 9) and BRD7 (bromodomain-containing protein 7). BI-9564 is sevenfold more effective on BRD9 and fourfold more effective on BRD7.[2]
BI-9564 is a cell permeable, potent and specific inhibitor of BRD9 and BRD7. For full characterization details, please visit the BI-9564 probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
 

特点和优势

BI-9564 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 

其他说明

BI-9564 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the BI-9564 probe summary on the Chemical Probes Portal website.
 
 

属性

质量水平

100

测定

≥97% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES string

CN1C=C(C2=CC(OC)=C(CN(C)C)C=C2OC)C(C=CN=C3)=C3C1=O

InChI

1S/C20H23N3O3/c1-22(2)11-13-8-19(26-5)15(9-18(13)25-4)17-12-23(3)20(24)16-10-21-7-6-14(16)17/h6-10,12H,11H2,1-5H3

InChI key

BJFSUDWKXGMUKA-UHFFFAOYSA-N

 

安全信息

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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