MabSelect Xtra抗体纯化层析树脂，MabSelect Xtra antibody purification chromatography resin

MabSelect Xtra antibody purification chromatography resin 抗体纯化层析树脂

MabSelect Xtra, with extra high dynamic binding capacity, is a protein A resin developed to meet the demands of increasing levels of expression in monoclonal antibody feedstocks.

比目前可用的蛋白 A 层析树脂具有更高的动态结合能力。
通过降低原材料成本和/或减少循环次数来提高工艺经济性。
由于高配体选择性和基质亲水性，高纯度捕获。
与 MabSelect SuRe 和 MabSelect 相比，压力/流动特性略低。
Resin 满足工业对供应安全性、强大性能和监管支持的需求。
孔隙率增加
MabSelect Xtra 具有与 MabSelect 相同的重组蛋白 A 配体，但基于高流动性琼脂糖基质，与 MabSelect 相比，具有更高的孔隙率和略微减小的粒径。这导致更高的容量——MabSelect Xtra 对 IgG 的动态结合容量比目前可用的蛋白 A 层析树脂高约 30%。

此外，MabSelect Xtra 对许多 Fc 融合蛋白具有更高的容量。

降低成本
与其他蛋白 A 树脂相比，MabSelect Xtra 树脂的总体生产成本较低，因为它可以以更少的批次处理浓缩原料。

• Higher dynamic binding capacity than currently available Protein A chromatography resins.
• Improved process economics through reduced raw materials costs and/or reduced number of cycles.
• High purity capture due to high ligand selectivity and matrix hydrophilicity.
• Slightly lower pressure/flow properties compared to MabSelect SuRe and MabSelect.
• Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.