GW2974，≥98% (HPLC), solid

图片 GW2974，≥98% (HPLC), solid
图片 GW2974，≥98% (HPLC), solid
图片 GW2974，≥98% (HPLC), solid
别名：N4-（1-苄基-1H-吲唑-5-基）-N6，N6-二甲基-吡啶­ [3,4-d] ­嘧啶-4,6-二胺；N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido­[3,4-d]­pyrimidine-4,6-diamine

Empirical Formula (Hill Notation): C23H21N7 CAS号: 202272-68-2 分子量: 395.46 MDL编号: MFCD04974495 PubChem化学物质编号: 24278451 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: G0668
CAS号: 202272-68-2
MDL号: MFCD04974495
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥2,718.26

说明

生化/生理作用

Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
 

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Glaxo­Smith­Kline
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

solid

颜色

yellow

溶解性

DMSO: ≥20 mg/mL

创始人

GlaxoSmithKline

SMILES string

CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1

InChI

1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28)

InChI key

DYYZXRCFCVDSKD-UHFFFAOYSA-N

Gene Information

human ... EGFR(1956) , ERBB2(2064)

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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