Fmoc-N'-甲基三苯甲基-L-赖氨酸，Fmoc-Lys(Mtt)-OH；Novabiochem®, ≥98%

图片 Fmoc-N'-甲基三苯甲基-L-赖氨酸，Fmoc-Lys(Mtt)-OH；Novabiochem®, ≥98%
别名：N-α-Fmoc-N-ε-4-甲基三苯甲基-L-赖氨酸；N-α-Fmoc-N-ε-4-methyltrityl-L-lysine；Fmoc-Lys(Mtt)-OH

Empirical Formula (Hill Notation): C41H40N2O4 CAS号: 167393-62-6 分子量: 624.77
制造商品牌: 默克 Merck , 西格玛 Sigma-Aldrich
货号（SKU）: 8.52065
CAS号: 167393-62-6
MDL号: MFCD00237166
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说明

一般描述

The side-chain Mtt group can be selectively removed with 1% TFA in DCM [1,2,3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis by Fmoc SPPS of branched peptides, peptides modified at the lysine side-chain [5,6], for the construction of templates and multifunctionalized resins for combinatorial synthesis.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references
[1] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283.
[2] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488.
[3] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264.
[4] K. Barlos, personal communication.
[5] P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436.
[6] C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257.
 

联系

Replaces: 04-12-1137
 

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.
 

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

质量水平

200

产品线

Novabiochem®

检测方案

≥95.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

形式

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

140-150 °C

application(s)

peptide synthesis

官能团

amine

储存温度

2-8°C

InChI

1S/C41H40N2O4/c1-29-23-25-32(26-24-29)41(30-14-4-2-5-15-30,31-16-6-3-7-17-31)42-27-13-12-22-38(39(44)45)43-40(46)47-28-37-35-20-10-8-18-33(35)34-19-9-11-21-36(34)37/h2-11,14-21,23-26,37-38,42H,12-13,22,27-28H2,1H3,(H,43,46)(H,44,45)/t38-/m0/s1

InChI key

YPTNAIDIXCOZAJ-LHEWISCISA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 2

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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