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FM-479,≥98% (HPLC)

别名:FM479;2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide, (E)-2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide, FM-381 Inactive Control

Empirical Formula (Hill Notation): C25H26N6O2 分子量: 442.51 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML1992
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$492.34

说明

生化/生理作用

FM-479 is an FM-381 structural analog that exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range of 100-300 nM. For characterization details of the active probe, FM-381, please visit the FM-381 probe summary on the Structural Genomics Consortium (SGC) website.

FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
 
FM-479 是一种 FM-381 结构类似物,当以 100-300 nM 的 FM-381 有效剂量范围使用时,对 JAK3 或其他激酶没有抑制效力。
 

特点和优势

FM-479 is a negative control for FM-381, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC
 

属性

测定

≥98% (HPLC)

形式

powder

颜色

yellow to orange

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES string

CN(C(/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(N(C)C=C4)C4=C3N2C5CCCCC5)=O)C

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16