FM-479 is an
FM-381 structural analog that exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range of 100-300 nM. For characterization details of the active probe, FM-381, please visit the
FM-381 probe summary on the Structural Genomics Consortium (SGC) website.
FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381,
click here.
To learn about other SGC chemical probes, visit
sigma.com/sgc