D-生物素 [维生素B7]，D-Biotin；tested according to Ph. Eur., 98.5 - 101.0 % (DRIED SUBSTANCE)

别名：维生素-B7；维生素H；辅酶R；D-促进素；Bios II；D-Biotin；Bios II；Coenzyme R；Vitamin B7；Vitamin H

Empirical Formula (Hill Notation): C10H16N2O3S CAS号: 58-85-5 分子量: 244.31 Beilstein: 86838 EC 号: 200-399-3 MDL编号: MFCD00005541 PubChem化学物质编号: 329751923 NACRES: NA.21

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 19606

CAS号: 58-85-5

MDL号: MFCD00005541

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目录规格.SKU-Variant

说明

生物素，也称为维生素B7或维生素H，是一种水溶性B复合维生素，含有一个由四氢噻吩环融合的脲环。它存在于几种食物中，如全谷物、坚果、豆类、未抛光的大米和蛋黄。正常的肠道菌群也会产生这种维生素。
生物素已用于标记猪抗兔IgG抗体和过氧化物酶。

生物素也称为维生素H或维生素B7，是一种水溶性B族维生素，可诱导大鼠肝脏、肾脏、结肠、小脑和心脏中鸟苷酸环化酶活性增加2至3倍。它还能刺激精子活力，延长冷冻保存的人类精子的存活时间。
生物素在几种代谢途径中充当羧化酶的重要辅因子。它在脂肪酸、异亮氨酸和缬氨酸的代谢中充当辅酶。生物素与糖异生和柠檬酸循环有关。它参与角蛋白合成，因此被用作皮肤、头发和指甲生长的补充。生物素促进细胞生长、脂肪酸的产生以及脂肪和氨基酸的代谢。它有助于二氧化碳的转移，并维持稳定的血糖水平。

一般描述

Biotin, also called vitamin B7 or vitamin H is a water-soluble B complex vitamin, which contains an uredo ring fused by a tetrahydrothiophene ring. It is found in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

应用

Biotin has been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

生化/生理作用

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Biotin functions as an important cofactor for carboxylase enzymes in several metabolic pathways. It acts as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin promotes cell growth, production of fatty acids and the metabolism of fats and amino acids. It assists the transfer of carbon dioxide and also sustains a steady blood sugar level.

属性

生物来源

synthetic

质量水平

200

Agency

tested according to Ph. Eur.

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 50 \| 欧洲Eur. ≥ 12 \| 東京Tokyo ≥ 20 \| 香港与北京 ≥ 50

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