亚精胺 [精脒]，Spermidine；BioReagent, for molecular biology, suitable for cell culture, ≥98%

General description

Spermidine belongs to the natural polyamines, that are found in chloroplasts and in bacterial or eukaryotic cells.^[4]

Application

Spermidine has been used in the preparation of gold beads^[6] and as a component in nuclei isolation buffer (NIB).^[7]

精胺适合用于分子生物缓冲液和> 100 bp DNA沉淀。它被用来在植物和哺乳动物细胞中，通过粒子轰击技术，传递DNA。^[1][2]

Biochem/physiol Actions

Spermidine helps to maintain the proper activity of gene expression.^[4] This polyamine plays a key role in intermediate metabolism. It also serves as an inhibitor of the acetyl transferase activity of E1A-associated protein p300 (EP300).^[3] Spermidine participates in cell growth.^[5]

抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA，可用于DNA结合蛋白纯化。激活T₄聚核苷酸激酶活性。

Caution

如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。

性质

安全信息

符号

  GHS05

信号词 Danger

危害声明 H314

警示性声明 P280 - P305 + P351 + P338 - P310

个人防护装备 Faceshields, Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

危害码 (欧洲) C

风险声明 (欧洲) 34

安全声明 (欧洲) 26-36/37/39-45

RIDADR UN 3259PSN2 8 / PGII

WGK德国 WGK 3

RTECS EJ7000000

闪点（华氏） 233.6 °F - closed cup

闪点（摄氏） 112 °C - closed cup