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D-(+)-海藻糖二水合物,D-(+)-Trehalose dihydrate;≥97.5% (by Assay), Calbiochem®

别名:α,α-海藻糖;α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷;二水海藻糖;D(+)-蕈糖;蕈糖;D-海藻糖二水合物; α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside

Empirical Formula (Hill Notation): C12H22O11 · 2H2O CAS号: 6138-23-4 分子量: 378.33 MDL编号: MFCD00071594
货号(SKU): 625625
CAS号: 6138-23-4
MDL号: MFCD00071594
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¥2,660.00

说明

酸水解后产生 2 摩尔 D-葡萄糖的非还原性二糖。 在体内和体外抑制聚谷氨酰胺介导的蛋白质聚集。 已证明口服海藻糖可有效延长小鼠亨廷顿病模型的寿命。 还已知在渗透压培养的细菌细胞中积累并防止脱水的不利影响。 据报道可防止肌红蛋白崩溃并保持其内部流动性。

Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
 

一般描述

Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
 

警告

Toxicity: Standard Handling (A)
 

其他说明

Sarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med.10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
 

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

质量水平

100

测定

≥97.5% (by Assay)

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze

溶解性

water: 100 mg/mL

痕量阳离子

Fe: <5 ppm
heavy metals: <10 ppm

运输

ambient

储存温度

15-25°C

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 1

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10
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