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BPTU,BMS-646786;≥98% (HPLC)

别名:N-[2-[2-(1,1-二甲基乙基)苯氧基]-3-吡啶基]-N'-[4-(三氟甲氧基)苯基]-脲;N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N′-[4-(trifluoromethoxy)phenyl]-urea

CAS号 870544-59-5 经验分子式(希尔表示法) C23H22F3N3O3 分子量 445.43 MDL number MFCD28386231 PubChem Substance ID 329774363 NACRES NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): BM0020
CAS号: 870544-59-5
MDL号: MFCD28386231
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₹ 13,002.81

产品描述

一种抑制人血中ADP介导的血小板聚集的PY1嘌呤受体的强效特异性抑制剂。

包装

5, 25 mg in glass bottle

Biochem/physiol Actions

BMS-646786 is a potent and specific inhibitor of P2Y1 purinergic receptor that inhibits ADP-mediated platelet aggregation in human blood samples. BMS-646786 significantly reduces thrombus weight in a rat arterial thrombosis model with a limited effect on bleeding.

BMS-646786是P2Y1嘌呤能受体的有效和特异性抑制剂,可抑制人血样中ADP介导的血小板聚集。 BMS-646786可在大鼠动脉血栓形成模型中显着降低血栓重量,对出血的作用有限。

Features and Benefits

BMS-646786 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

Legal Information

Sold for research purposes only under agreement from BMS.

性质

Quality Level  100
assay  ≥98% (HPLC)
form  powder
storage condition  protect from light
color  white to beige
solubility  DMSO: 20 mg/mL, clear
storage temp.  room temp
SMILES string  O=C(NC1=CC=C(OC(F)(F)F)C=C1)NC2=C(OC3=CC=CC=C3C(C)(C)C)N=CC=C2
InChI  1S/C23H22F3N3O3/c1-22(2,3)17-7-4-5-9-19(17)31-20-18(8-6-14-27-20)29-21(30)28-15-10-12-16(13-11-15)32-23(24,25)26/h4-14H,1-3H3,(H2,28,29,30)
InChI key  AHFLGPTXSIRAQK-UHFFFAOYSA-N


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32