BAY-677 is the negative control probe for BAY-678
, which is a human neutrophil elastase (HNE) inhibitor with >2,000-fold selectivity for HNE over a panel of 21 other serine proteases. For characterization details of BAY-678 and BAY-677, please visit the BAY-677 probe summary
on the Structural Genomics Consortium (SGC) website.
BAY-678, the active HNE probe, is available from Sigma. To learn more about and purchase BAY-678, click here
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
BAY-677 是 BAY-678 的阴性对照探针，BAY-678 是一种人类中性粒细胞弹性蛋白酶 (HNE) 抑制剂，对 HNE 的选择性是 21 种其他丝氨酸蛋白酶的 2,000 倍以上。