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BAY-677,≥98% (HPLC)

别名:5-{(4S)-5-Acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}pyridine-2-carbonitrile, 2-Pyridinecarbonitrile, 5-[(4S)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-, (S)-BAY-678

Empirical Formula (Hill Notation): C20H15F3N4O2 分子量: 400.35 PubChem化学物质编号: 329825967 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML1564
CAS号: 2117404-84-7
增值税发票 √ 免费送货 √ 订货电话:010-68689484
$233.74

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

BAY-677 is the negative control probe for BAY-678, which is a human neutrophil elastase (HNE) inhibitor with >2,000-fold selectivity for HNE over a panel of 21 other serine proteases. For characterization details of BAY-678 and BAY-677, please visit the BAY-677 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-678, the active HNE probe, is available from Sigma. To learn more about and purchase BAY-678, click here.
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
 
BAY-677 是 BAY-678 的阴性对照探针,BAY-678 是一种人类中性粒细胞弹性蛋白酶 (HNE) 抑制剂,对 HNE 的选择性是 21 种其他丝氨酸蛋白酶的 2,000 倍以上。
 

特点和优势

BAY-677 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

旋光性

[α]/D -21 to -29°, c = 0.5 in methanol

颜色

white to light brown

溶解性

DMSO: 20 mg/mL, clear

储存温度

2-8°C

SMILES string

CC(N1C2=CC=CC(C(F)(F)F)=C2)=C(C(C)=O)[C@H](C3=CN=C(C#N)C=C3)NC1=O

InChI

1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m0/s1

InChI key

PGIVGIFOWOVINL-SFHVURJKSA-N

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16