甲萘醌 [维生素K3]，Menadione；Pharmaceutical Secondary Standard; Certified Reference Material

图片 甲萘醌 [维生素K3]，Menadione；Pharmaceutical Secondary Standard; Certified Reference Material
别名：维生素K3标准品；甲萘醌标准品；维他命K3；Vitamin K3；VK3；2-甲基-1,4-萘醌；2-甲基-1,4-萘酚喹酮；维生素-K3；亚硫酸氢钠甲萘醌；2-甲基-1,4-萘醌；亚硫酸氢钠甲萘醌（MSB）；二甲基嘧啶醇亚硫酸甲萘醌（亚硫酸二甲嘧啶甲萘醌MPB）；亚硫酸烟酰胺甲萘醌（MNB）；亚硫酸氢钠甲萘醌复合物（MSBC）；抗出血维生素；2-Methyl-1,4-naphthoquinone

Empirical Formula (Hill Notation): C11H8O2 CAS号: 58-27-5 分子量: 172.18 Beilstein: 1908453 EC 号: 200-372-6 MDL编号: MFCD00001681 PubChem化学物质编号: 329823383 NACRES: NA.24
制造商品牌: 西格玛 Sigma-Aldrich , 色谱科 Supelco
货号（SKU）: PHR1411
CAS号: 58-27-5
MDL号: MFCD00001681
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥1,192.65

说明

用于质量控制的制药二级标准，为制药实验室和制造商提供了一种方便且成本效益高的替代方案，以替代内部工作标准的制定。
甲萘酮是一种抗出血化合物，它作为一种重要的辅助因子在凝血和骨代谢中得到应用。此外，在相对较高的剂量下，甲萘醌对几种人类癌细胞表现出抗肿瘤活性。
甲萘酮可用作通过色谱法和分光光度法测定药物制剂中分析物的药物参考标准。

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Menadione is an antihemorrhagic compound and it finds application in blood clotting and bone metabolism as an essential cofactor. Additionally, at relatively higher dose, menadione exhibits antitumor activity on several human cancer cells.
 

应用

Menadione may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric methods.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAA2475 in the slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. M0300000
traceable to USP 1381006

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

105-107 °C (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES string

CC1=CC(=O)c2ccccc2C1=O

InChI

1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

InChI key

MJVAVZPDRWSRRC-UHFFFAOYSA-N

 

安全信息

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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