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氨苄青霉素 [氨苄西林三水合物]，Ampicillin trihydrate；Pharmaceutical Secondary Standard; Certified Reference Material

别名：三水合氨苄青霉素；氨苄青霉素三水合物；D-(−)-α-Aminobenzylpenicillin；安比西林；氨苄青霉素；安比林；安比先；安必林；安必仙；安必欣；氨西林；氨苄青；氨苄三水酸；三水合氨苄青霉素；氨苄青霉素三水酸；氨苄青霉素三水物；苄那消；amfipen；qidamp；ay-6108；Ampicillin；binotal；2S， 5R，6R)-3，3-二甲基-6-〔（R)-2-氨基-2-苯乙酰氨基〕-7-氧代-4-硫杂-1-氮杂双环[3.2.o]庚烷-2-甲酸三水化合物

Empirical Formula (Hill Notation): C16H19N3O4S · 3H2O CAS号: 7177-48-2 分子量: 403.45 Beilstein: 5399534 EC 号: 200-709-7 MDL编号: MFCD00072036 PubChem化学物质编号: 329823367 NACRES: NA.24

制造商品牌: 西格玛 Sigma-Aldrich , 默克色谱科 Supelco

货号（SKU）: PHR1393

CAS号: 7177-48-2

MDL号: MFCD00072036

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目录价.SKU-Variant

¥1,150.00

数量:

说明

用于质量控制的制药二级标准，为制药实验室和制造商提供了一种方便且成本效益高的替代方案，以替代内部工作标准的制定。
三水合氨苄西林可用作通过色谱技术测定血浆样品和药物制剂中氨苄西林的分析参考标准。

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Ampicillin trihydrate may be used as an analytical reference standard for the determination of ampicillin in plasma samples and pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

一种具有连接到青霉素结构上的氨基侧链的 β-内酰胺抗生素。通过灭活细菌细胞膜内表面的转肽酶而抑制细菌细胞壁合成（肽聚糖交联）的青霉素衍生物。仅对生长中的大肠埃希菌具有杀菌作用。耐药方式：氨苄西林的 β-内酰胺环被 β-内酰胺酶裂解。抗菌谱：革兰阴性菌和革兰阳性菌。

附注

To see an example of a Certificate of Analysis for this material enter LRAA1900 in the slot below. This is an example certificate only and may not be the lot that you receive.

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 785
traceable to Ph. Eur. A1000000
traceable to USP 1033000/1033407

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

198-200 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

RXDALBZNGVATNY-CWLIKTDRSA-N

安全信息

象形图

GHS07,GHS08

警示用语：

Danger

危险声明

H315 - H317 - H319 - H334 - H335

预防措施声明

P261 - P264 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 99 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 22 \| 香港与北京 ≥ 32

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