过滤
关闭导航

氨基-PEG6-叔丁酯,Amino-PEG6-t-butyl ester;liquid

别名:tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate, H2N-PEG6-CH2CH2COOtBu

Empirical Formula (Hill Notation): C19H39NO8 CAS号: 1286281-32-0 分子量: 409.51 MDL编号: MFCD13184944
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 902659
CAS号: 1286281-32-0
MDL号: MFCD13184944
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥1,407.06

说明

应用

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
 

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
 
 

属性

形式

liquid

reaction suitability

reagent type: cross-linking reagent

折射率

n/D 1.4562

密度

1.06581 g/mL

官能团

amine
ester

储存温度

−20°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O

InChI

1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3

InChI key

QGSFECNPSLZGGT-UHFFFAOYSA-N

 

安全信息

储存分类代码

10 - Combustible liquids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30