异柠檬脱氢酶 (NADP) 来源于猪心脏，Isocitric Dehydrogenase (NADP) from porcine heart [ICDH, IDH]；Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein

图片 异柠檬脱氢酶 (NADP) 来源于猪心脏，Isocitric Dehydrogenase (NADP) from porcine heart [ICDH, IDH]；Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
别名：异柠檬脱氢酶 (NADP)；ICDH；IDH；苏式-Ds-异柠檬酸: NADP+ 氧化还原酶；异柠檬酸脱氢酶胞质；Isocitrate Dehydrogenase Cytoplasmic

CAS号: 9028-48-2 EC 号: 1.1.1.42 (BRENDA, IUBMB) EC 号: 200-289-5 MDL编号: MFCD00131420 NACRES: NA.54
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: I2002
CAS号: 9028-48-2
MDL号: MFCD00131420
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说明

应用

Isocitric dehydrogenase (IDH) has been used:
  • for in vitro activity assay to study the effects of thorium on citric acid cycle enzymes in the mitochondrial respiration pathway[1]
  • as a standard to measure the impact of temperature on nicotinamide diphosphate (NADP)-IDH activity[2]
  • in isocitrate assay[3]

生化/生理作用

Isocitrate dehydrogenase (IDH) is a homodimeric enzyme and participates in several processes such as adapting to hypoxia, histone demethylation, and DNA modification. This enzyme has three isoforms like IDH1, IDH2, and IDH3.[4]
 

单位定义

在37℃条件下，当pH为7.4时，一个单位每分钟将1.0 μ摩尔的异柠檬酸盐转化为至α-酮戊二酸。
 

外形

50%甘油EDTA缓冲盐溶液，pH 6.0
 
 

属性

类型

Type IV

质量水平

200

形式

buffered aqueous glycerol solution

质量

≤ 0.2% of main activity is obtained with NAD as cofactor.

specific activity

3-20 units/mg protein

组成

Protein biuret

运输

wet ice

储存温度

2-8°C

 

安全信息

储存分类代码

10 - Combustible liquids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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