IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。 它由B细胞分泌，存在于血液和细胞外液中，可防止细菌，真菌和病毒引起的感染。 母体IgG通过胎盘转移到胎儿，这对新生儿抵抗感染的免疫防御至关重要。 IgG3具有独特的延伸铰链区，赋予更大的灵活性来自鼠类骨髓瘤的IgG3，κ特异性识别小鼠IgG3。 小鼠IgG3，κ的特异性通过免疫扩散和IEP技术确定。 纯化的骨髓瘤制剂与小鼠IgA，IgM，IgD，IgG1，IgG2a和IgG2b的抗血清无反应。
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG3 is the has a unique extended hinge region conferring greater flexibility
IgG3, κ from murine myeloma specifically recognizes mouse IgG3. Specificity of the mouse IgG3, κ is determined by immunodiffusion and IEP techniques. The purified myeloma preparation is non-reactive with antisera to mouse IgA, IgM, IgD, IgG1, IgG2a and IgG2b.
IgG3, κ from murine myeloma was used as blocking agent in immunofluorescence labeling of larval and adult Echinococcus multilocularis worms. It was used as negative control in assay to study the surface binding of antibodies to meningococci.
Solution in Tris buffered saline, pH 7.2, containing 0.1% sodium azide.
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|antibody form||purified immunoglobulin|
|assay||≥95% (microfluidic capillary gel electrophoresis)|
|form||buffered aqueous solution|
|shipped in||dry ice|
RIDADR NONH for all modes of transport