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头孢噻肟钠盐 [噻孢霉素],Cefotaxime sodium salt;≥97% (HPLC), suitable for cell culture, Calbiochem®

别名:头孢霉素;头孢赛肟钠盐;头孢噻吩钠盐;Cefotaxim sodium salt;7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7²-(Z)-(O-methyloxime) Acetate, Na, Cefotaxim sodium salt

CAS号 64485-93-4 经验分子式(希尔表示法) C16H16N5NaO7S2 分子量 477.45 Beilstein/REAXYS Number 5711411 MDL number MFCD00079073
货号(SKU): 219504
CAS号: 64485-93-4
MDL号: MFCD00079073
增值税发票 √ 免费货运 [顺丰 联邦] √
¥1,660.00

产品描述

头孢噻肟钠盐, 属第三代头孢类抗生素

General description

Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.

包装

1, 5 g in Glass bottle

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Primary Target
Gram-positive

Secondary Target
Gram-negative

包装

Packaged under inert gas

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

Molinari, G., et al. 1991. J. Chemotherap.3, 6.
Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother.35, 2057.

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

性质

Quality Level100
assay≥97% (HPLC)
formpowder
mfr. no.Calbiochem®
storage conditionOK to freeze
desiccated
protect from light
storage conditions+15C to +30C
application(s)cell culture | mammalian: suitable
colorwhite
solubilitywater: 1 mg/mL
shipped inambient
SMILES string[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
InChI1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
InChI keyAZZMGZXNTDTSME-JUZDKLSSSA-M


安全信息

符号
GHS08  GHS08
信号词 Danger
危害声明 H317 - H334
警示性声明 P261 - P280 - P342 + P311
危害码 (欧洲) Xn
风险声明 (欧洲) 42/43
安全声明 (欧洲) 22-36/37
RIDADR NONH for all modes of transport
WGK德国 WGK 2
RTECS XI0250000
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62