头孢噻肟钠盐 [噻孢霉素]，Cefotaxime sodium salt；≥97% (HPLC), suitable for cell culture, Calbiochem®

General description

Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.

包装

1, 5 g in Glass bottle

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Primary Target
Gram-positive

Secondary Target
Gram-negative

包装

Packaged under inert gas

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

Molinari, G., et al. 1991. J. Chemotherap.3, 6.
Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother.35, 2057.

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

性质

安全信息

符号

  GHS08

信号词 Danger

危害声明 H317 - H334

警示性声明 P261 - P280 - P342 + P311

个人防护装备 dust mask type N95 (US), Eyeshields, Faceshields, Gloves

危害码 (欧洲) Xn

风险声明 (欧洲) 42/43

安全声明 (欧洲) 22-36/37

RIDADR NONH for all modes of transport

WGK德国 WGK 2

RTECS XI0250000