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L-丙氨酰基-L-1-氨基乙基膦酸,L-Alanyl-L-1-aminoethylphosphonic acid;≥95% (HPLC)

别名:阿拉磷素;(S)-丙氨酸基-(R)-1-氨基乙基膦酸;阿拉福伐林;丙氨酸膦;(S)-Alanyl-(R)-1-aminoethylphosphonic acid, Alafosfalin, Alaphosphin

Empirical Formula (Hill Notation): C5H13N2O4P CAS号: 60668-24-8 分子量: 196.14 Beilstein: 4801790 EC 号: 262-362-8 MDL编号: MFCD01569244 PubChem化学物质编号: 329747669 NACRES: NA.85
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 05260
CAS号: 60668-24-8
MDL号: MFCD01569244
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说明

化学结构:氨基酸衍生物
阿拉磷素被用作沙门氏菌分离的选择剂和二肽模拟抗菌剂。
阿拉磷素是一种抗菌磷肽,它模拟细菌细胞壁肽聚糖的末端二肽部分(D-Ala-D-Ala)。它代谢抑制丙氨酸外消旋酶和尿苷5-二磷酸-N-乙酰基尿苷丙氨酸合成酶的氨基膦酸。
阿拉磷素被用作沙门氏菌分离的选择剂和二肽模拟抗菌剂。它代谢抑制丙氨酸外消旋酶和尿苷5-二磷酸-N-乙酰基尿苷丙氨酸合成酶的氨基膦酸。

一般描述

Chemical structure: amino acid derivatives
 

应用

Alaphosphin is used as a selection agent for isolation of Salmonella and as a dipeptide mimetic antibacterial agent.
 

生化/生理作用

Alaphosphin is an antibacterial phosphonopeptide which mimics the terminal dipeptide moiety (D-Ala-D-Ala) of bacterial cell wall peptidoglycan . It metabolizes aminophosphonic acid which inhibits alanine racemase and uridine 5-diphosphate-N-acetylmuramoylalanine synthetase.
Alaphosphin is used as a selection agent for isolation of Salmonella and as a dipeptide mimetic antibacterial agent. It metabolizes aminophosphonic acid which inhibits alanine racemase and uridine 5-diphosphate-N-acetylmuramoylalanine synthetase.
 

其他说明

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Moisture sensitive. Keep in a dry place.
 
 

属性

质量水平

200

测定

≥95% (HPLC)

形式

powder

旋光性

[α]20/D −45±2°, c = 1% in H2O

颜色

white

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell wall synthesis | interferes
enzyme | inhibits

储存温度

2-8°C

SMILES string

C[C@H](N)C(=O)N[C@@H](C)P(O)(O)=O

InChI

1S/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1

InChI key

BHAYDBSYOBONRV-IUYQGCFVSA-N

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16