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单宁酸 [没食子鞣酸],Tannic acid [TA];puriss., meets analytical specification of USP, powder

别名:Tannin;Gallotannin; Empirical Formula (Hill Notation): C76H52O46 CAS号: 1401-55-4 分子量: 1701.20 Beilstein: 8186396 EC 号: 215-753-2 MDL编号: MFCD00066397 PubChem化学物质编号: 329751144 NACRES: NA.21
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 16201
CAS号: 1401-55-4
MDL号: MFCD00066397
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥646.52

说明

一般描述

Tannic acid is the simplest hydrolyzable tannin. The chemical structure of tannic acid has a glucose molecule in its core connected to 10 galloyls groups via aliphatic ester bonds. TA is one of the most abundant natural polyphenols, which can be colorless to yellow in color, and of astringent taste. It can be sourced from the bark of oak, chestnut, hemlock, mangrove, etc.
 

应用

Tannic acid has been used:
  • as a reference standard to measure the total hydrolyzable tannins in Oak root bark tannin-methanol extract using a UV/Vis spectrophotometer
  • as a blood-brain barrier (BBB) impermeable, transcytosis-inhibiting drug in spheroid culture medium
  • as a flushing agent to test its effects on metal ions, total organic carbon, and organic matter of soil
  • as an inhibitor of free ovalbumin (OVA) uptake by the endocytic mechanism on dendritic cells

生化/生理作用

Tannic acid has many pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumor effects. It also exerts anti-aging, wound healing, and neuroprotective activities. TA is traditionally used as a tanning agent in the food, leather, adhesive, and pharmaceutical industries. It is a natural crosslinker that is useful in building polymeric networks and can be used to design biomedical hydrogels.
 
 

属性

等级

puriss.

质量水平

形式

powder

自燃温度

980 °F

质量

meets analytical specification of USP

杂质

dextrines, gum matters, in accordance
resinous matters, in accordance
≤0.003% heavy metals (as Pb)

灼烧残渣

≤0.1% (as SO4)

缺失

≤9% loss on drying, 105 °C, 2 h

mp

218 °C (lit.)

溶解性

H2O: soluble 1 gm in 0.35ml
glycerol: soluble 1gm in 1 ml (warm)
acetone: very soluble
alcohol: freely soluble (Diluted)
alcohol: slightly soluble (Dehydrated)
alcohol: very soluble
benzene: insoluble
carbon disulfide: insoluble
carbon tetrachloride: insoluble
chloroform: insoluble
diethyl ether: insoluble
hexane: insoluble
petroleum ether: insoluble

痕量阳离子

As: ≤3 mg/kg

SMILES string

Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10

InChI

1S/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1

InChI key

LRBQNJMCXXYXIU-PPKXGCFTSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

390.2 °F

闪点(C)

199 °C

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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