人血清白蛋白 [人白蛋白]，Albumin human [rHSA]；lyophilized powder, essentially fatty acid free, ≥96% (agarose gel electrophoresis)

General description

Albumin is the most abundant plasma protein in human. It has a molecular weight of 66.5 kDa.^[10]

Application

Albumin from human serum has been used:
• as a carrier of CPT-11 (irinotecan, Campto) and SN-38 to investigate its binding to human plasma proteins^[7]
• to study the adsorption of water and acetonitrile (AN) vapor on a human serum albumin^[8]
• to study its effect on wound healing process^[9]

包装

1, 5, 10, 25 g in poly bottle

100, 500 mg in poly bottle

Biochem/physiol Actions

Serum albumin primarily mediates divalent cation transportation, fatty acid and drug complex formation and transport.^[6] The albumin levels in the serum indicate the disease progression in advanced liver disease.^[10] Low body weight and decreased serum albumin is associated with colorectal cancer.^[5]

血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白，对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质，特别是药物（例如布洛芬、华法林），并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。

Preparation Note

Prepared from albumin (A1653)

Other Notes

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性质

安全信息