General description
三(2-羧乙基)膦盐酸(TCEP.HCl)是一种非挥发性的固体。它是一种强还原剂。1[4]它可通过在回流的HCl水溶液中对三(2-氰基乙基)膦进行酸水解而合成。1[4]它具有多种生物学应用,例如多种肽和蛋白质中二硫键的体内及体外还原。1 TCEP可用作多种重金属离子如Zn(II), Cd(II), Pb(II)以及Ni(II)的螯合剂。[5]Application
Tris(2-carboxyethyl)phosphine hydrochloride (TCEP. HCl) can be employed as a reducing agent for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It can also be used in azide-alkyne cycloaddition reaction in the presence of a copper catalyst.[6]
In biological applications, TCEP is widely used to reduce disulfide bonds in various proteins.[6]水溶性试剂,用于二硫化物的选择性还原。在质谱应用中比 DTT 更稳定。
包装
2, 10, 50 g in glass bottle
Caution
储存条件:干燥储存。