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VIII因子纯选亲和层析树脂,VIIISelect

VIIISelect 是一种亲和层析树脂,设计用于纯化重组 β 结构域耗尽的因子 VIII。17545001;17545002;17545004
货号(SKU): 17545002
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥914,483

VIIISelect is an affinity chromatography resin designed for the purification of recombinant β domain depleted factor VIII.

对重组 β 结构域缺失的因子 VIII 具有高度选择性
以高产率和保留活性的重组 β 结构域缺失因子 VIII 的高效纯化
优秀的可扩展性
非动物来源
VIIISelect 是一种亲和树脂,设计用于纯化重组 β 结构域缺失的 VIII 因子,这是一种用于治疗 A 型血友病的关键重组血液因子。 由于 VIII 因子分子的敏感性,限制步骤数很重要 在下游过程中。 使用 VIIISelect 获得的高选择性和高产率可实现稳健高效的纯化过程,一步即可获得出色的纯度。

  • Highly selective for recombinant β-domain-deleted Factor VIII
  • Efficient purification of recombinant β-domain-deleted Factor VIII with high yields and retained activity
  • Excellent scalability
  • Non-animal derived

VIIISelect is an affinity resin designed for the purification of recombinant β-domain-deleted factor VIII, a key recombinant blood factor used for treatment of Hemophilia A. Due to the sensitive nature of the factor VIII molecule it is important to limit the number of steps in the downstream process. The high selectivity and yields obtained using VIIISelect enable a robust and efficient purification process with excellent purity obtained in one step.

 

ParameterVIIISelect, 500 mL
Order InformationThis product is produced based on a customer order. Delivery time may be longer than for standard products. 
Chromatography techniqueGroup specific affinity 
BioProcess resinYes 
LigandMr 13 000 recombinant protein produced in S. cerevisiae. Binds to β domain deleted factor VIII molecules. 
Particle size, d50V1~75 µm 
MatrixHighly crosslinked agarose 
Ligand Coupling MethodAmide linkage 
Binding Capacity/ml Chromatography Medium> 20000 IU / Ml 
Ligand densityApprox. 0.7 mg/mL of resin 
pH stability, operational23–10 
pH stability, CIP32–12 
Pressure/Flow Specification< 300 cm/h, < 200 kPa, BPG 300, bed height 20 cm 
Coupling ChemistryNHS 
Storage4 to 8°C, 20% Ethanol 
Chemical stabilityStable to commonly used aqueous buffers 
Pack size500 mL 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32