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VII因子纯选亲和层析树脂,VIISelect

VIISelect 是一种亲和层析树脂,设计用于纯化因子 VII/VIIa。17547703;17547701;17547702
货号(SKU): 17547703
增值税发票 √ 免费送货 √ 订货电话:010-68689484
₹ 2,44,692.89

VIISelect is an affinity chromatography resin designed for the purification of Factor VII/VIIa

用于高效工业纯化因子 VII 的高选择性亲和层析树脂
刚性琼脂糖基质允许高流速和大体积样品处理以提高通量
非哺乳动物衍生产品减少监管问题
在血友病患者治疗的开发中需要用于纯化重组凝血因子的有效方法。 VIISelect 是一种亲和树脂,设计用于纯化因子 VII/VIIa,因子 VII/VIIa 是一种血液因子,用于治疗已开发出替代凝血因子抑制剂的血友病患者。 它可以在温和的洗脱条件下用于从血浆和重组来源中纯化因子 VII。

  • Affinity chromatography resin with high selectivity for efficient industrial purification of Factor VII
  • Rigid agarose base matrix allows high flow rates and processing of large sample volumes for increased throughput
  • Non-mammalian derived product reduces regulatory concerns

Efficient processes for the purification of recombinant blood coagulation factors are needed in the development of treatments for hemophilia patients. VIISelect is an affinity resin designed for the purification of Factor VII/VIIa, a blood factor used for treatment of hemophilia patients who have developed inhibitors against replacement coagulation factors. It can be used, under mild elution conditions, for purifying Factor VII from plasma as well as from recombinant sources.

 

ParameterVIISelect, 1l
Chromatography techniqueGroup specific affinity 
BioProcess resinNo 
LigandRecombinant protein (Mr 14 080) produced in Saccharomyces cerevisiae 
Particle size, d50V1~75 µm 
MatrixHighly cross-linked, high-flow agarose 
Ligand densityApprox. 5.7 mg/ml of medium 
pH stability, operational23–10 
pH stability, CIP32–12 
Pressure/Flow SpecificationAt least 600 cm/h in a 1 m column with 20 cm bed height at 20°C using process buffers with the same viscosity as water at < 3bar (0.3 Mpa) 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32