sevenspikes.themes.common.filters
sevenspikes.themes.common.closemenu

UNC926,≥98% (HPLC)

别名:(3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone;(3-溴苯基)(4-(吡咯烷基-1-基)哌啶-1-基)甲酮

CAS号 1184136-10-4 经验分子式(希尔表示法) C16H21BrN2O 分子量 337.25 MDL number MFCD23098916 PubChem Substance ID 329825550 NACRES NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML0554
CAS号: 1184136-10-4
MDL号: MFCD23098916
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥1,053.47

产品描述

一种甲基-赖氨酸的L3MbTL1的特异性拮抗剂, IC50:3.9 μM。

包装

5, 25 mg in glass bottle

Biochem/physiol Actions

UNC926 is a specific antagonist of the methyl-lysine binding protein L3MBTL1, a member of a protein family that reads the methylation state of histone lysine residues to direct gene expression. UNC926 dose dependently blocks the interaction of recombinant L3MBTL carrying three tandem MBT reader domains (L3MBTL3XMBT) and a methylated histone peptide H4K20me1 with an IC50 of 3.9 μM.

性质

Quality Level  100
assay  ≥98% (HPLC)
form  powder
color  white to light brown
solubility  DMSO: 2 mg/mL, clear (warmed)
storage temp.  2-8°C
SMILES string  Brc1cccc(c1)C(=O)N2CCC(CC2)N3CCCC3
InChI  1S/C16H21BrN2O/c17-14-5-3-4-13(12-14)16(20)19-10-6-15(7-11-19)18-8-1-2-9-18/h3-5,12,15H,1-2,6-11H2
InChI key  OWGLFIKZKQOYHZ-UHFFFAOYSA-N


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16