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TWEAK Receptor human,[FGF-inducible 14, TNFRSF12A];recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

别名:FGF-inducible 14, TNF-related weak inducer of apoptosis receptor, TNFRSF12A;NACRES NA.32
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SRP3180
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¥3,574.00

产品描述

General description

TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic "death domain," which can activated the cell’s apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein

Biochem/physiol Actions

TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic "death domain," which can activated the cell’s apoptotic machinery. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein

Sequence

EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP

Physical form

Lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 50 mM NaCl.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

性质

biological source  human
recombinant  expressed in E. coli
assay  ≥98% (HPLC)
 ≥98% (SDS-PAGE)
form  lyophilized
potency  1.0-3.0 μg/mL ED50
mol wt  5.6 kDa
packaging  pkg of 25 μg
application(s)  cell culture | mammalian: suitable
impurities  <0.1 EU/μg endotoxin, tested
color  white
UniProt accession no.  Q9NP84
shipped in  wet ice
storage temp.  −20°C
Gene Information  human ... TNFRSF12A(51330)


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16