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Toceranib,≥98% (HPLC)

别名:SU11654, PHA-291639, SU-11654, 5-(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl-2,4-dimethyl-N-2-(pyrrolidin-1-yl)ethyl-1H-pyrrole-3-carboxamide

Empirical Formula (Hill Notation): C22H25FN4O2 CAS号: 356068-94-5 分子量: 396.46
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0338
CAS号: 356068-94-5
MDL号: MFCD16038046
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$233.74

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

Toceranib (SU11654) is a protein tyrosine kinase inhibitor that selectively targets stem cell factor receptor c-kit, including all forms of mutant Kit, as well as PDGFR and VEGFR. Toceranib exhibited Ki values of 5 nM for PDGFR and 6 nM for VEGFR. Toceranib phosphate is approved for use in mast cell cancer in dogs.
 
Toceranib (SU11654) 是一种蛋白酪氨酸激酶抑制剂,可选择性靶向干细胞因子受体 c-kit,包括所有形式的突变 Kit,以及 PDGFR 和 VEGFR。 Toceranib 对 PDGFR 的 Ki 值为 5 nM,对 VEGFR 的 Ki 值为 6 nM。 Toceranib 磷酸盐被批准用于治疗犬肥大细胞癌。
 

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

yellow to orange

溶解性

DMSO: 2 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

RIDADR

NONH for all modes of transport

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16