Toceranib，≥98% (HPLC)

图片 Toceranib，≥98% (HPLC)
别名：SU11654, PHA-291639, SU-11654；5-(5Z)-(5-氟-2-氧代-1,2-二氢-3H-吲哚-3-亚基)甲基]-2,4-二甲基-N-[2-(吡咯烷-1-基)乙基]-1H-吡咯-3-甲酰胺；5-(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl-2,4-dimethyl-N-2-(pyrrolidin-1-yl)ethyl-1H-pyrrole-3-carboxamide

Empirical Formula (Hill Notation): C22H25FN4O2 CAS号: 356068-94-5 分子量: 396.46
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0338
CAS号: 356068-94-5
MDL号: MFCD16038046
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说明

生化/生理作用

Toceranib (SU11654) is a protein tyrosine kinase inhibitor that selectively targets stem cell factor receptor c-kit, including all forms of mutant Kit, as well as PDGFR and VEGFR. Toceranib exhibited Ki values of 5 nM for PDGFR and 6 nM for VEGFR. Toceranib phosphate is approved for use in mast cell cancer in dogs.
 

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

yellow to orange

溶解性

DMSO: 2 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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