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(S,R,S)-AHPC盐酸盐,(S,R,S)-AHPC hydrochloride;≥97%

别名: (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, E3 Ligase ligand, Ligand for PROTAC® research, VH032 Empirical Formula (Hill Notation): C22H30N4O3S · xHCl CAS号: 1448189-80-7 分子量: 430.56 (free base basis) MDL编号: MFCD30502992
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 901490
CAS号: 1448189-80-7
MDL号: MFCD30502992
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¥4,303.88

说明

应用

(S,R,S)-AHPC (HCl salt) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This (S,R,S) conformation is the active variant, and (S,S,S) is the inactive derivative (cat#901487) used as a negative control.
 

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
 
 

属性

质量水平

检测方案

≥97%

形式

powder or crystals

reaction suitability

reagent type: ligand

储存温度

2-8°C

SMILES string

N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C.Cl

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30