SP琼脂糖凝胶XL,SP Sepharose XL [GE Cytiva]

SP Sepharose XL是一种强阳离子交换剂,设计用于从澄清的原料中捕获生物分子的步骤。订货号:17507305;17507360;17507301;17507304;17-5073-05;17-5073-60;17-5073-01;17-5073-04
货号(SKU): 17507301
MDL号: MFCD00148494
增值税发票 √ 免费货运 [顺丰 联邦] √


SP Sepharose XL is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.

SP 琼脂糖凝胶 ® 用于蛋白质色谱、离子交换色谱和阳离子交换介质。SP琼脂糖凝胶® 已被用于姜科植物根茎中抑制蛋白和多肽的研究以及大豆碱性 7S 球蛋白亚基异质性和分子进化的研究。此外,SP 琼脂糖凝胶 ® 还有助于推动壳寡糖制备的工业应用。


SP Sepharose XL is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.

  • High loading capacities give more productive capture from clarified feedstocks.
  • Strong cation exchanger designed for capture steps
  • High chemical stability for effective CIP/sanitization
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.

SP Sepharose XL is based on a highly cross-linked, bead formed 6% agarose matrix similar to the well established SP Sepharose Fast Flow resin. Dextran chains are covalently coupled to the agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates

With its high loading capacities and excellent physical and chemical stability, SP Sepharose XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.

As member of the BioProcess resins range, SP Sepharose XL meets industrial demands with security of supply and comprehensive technical and regulatory support.


ParameterSP Sepharose XL
BioProcess resinYes 
Particle size, d50V1~90 μm 
Ion Exchanger TypeStrong cation exchanger 
Matrix6% cross-linked agarose with dextran surface extenders 
Particle Size45 μm-165 μm 
Ligand Coupling MethodDextran extenders through ether bonds 
Ionic Capacity0.18-0.25 mmol H+/ml medium 
pH stability, operational24–13 
pH stability, CIP33–14 
Pressure/Flow Specification300-500 cm/h 
Storage4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate 
Chemical stabilityCommonly used buffers, nonionic detergents, 1 M NaOH, 6 M guanidine hydrochloride 
Certificate of AnalysisYes 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.


个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK德国 3
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55