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rmp蛋白A琼脂糖凝胶FF，rmp Protein A Sepharose Fast Flow

rmp Protein A Sepharose Fast Flow是一种低泄漏、基于非哺乳动物的亲和树脂，设计用于实验室和工艺规模的单克隆和多克隆抗体的高纯度分离。17513801；17513802；17513803；17513805；17-5138-01；17-5138-02；17-5138-03；17-5138-05

制造商品牌: (安)法玛西亚 Amersham Pharmacia , 思拓凡 Cytiva

货号（SKU）: 17513803

增值税发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

5mL
25mL [+¥23,650.00]
200mL [+¥177,750.00]

¥9,850.00

数量:

rmp Protein A Sepharose Fast Flow

rmp Protein A Sepharose Fast Flow is a low leakage, non-mammalian based affinity resin designed for high purity separation of monoclonal and polyclonal antibodies at the laboratory and process scales.

通过化学稳定的酰胺键多点连接 rProtein A
使蛋白质 A 配体泄漏最小化的偶联化学。
rmp Sepharose 4 Sepharose Fast Flow 由重组蛋白 A 组成，通过还原胺化作用与完善的 Sepharose 4 Fast Flow 基础基质偶联，形成多点连接。

还原胺化产生化学稳定的酰胺键并导致配体泄漏率低。 rmp Protein A Sepharose 4 Fast Flow 的生产不使用动物源性成分。

作为 BioProcess 树脂系列的一员，rmp Sepharose 4 Fast Flow 能够满足工业需求，提供安全的供应以及全面的技术和法规支持。

Multi-point attachment of rProtein A by chemically-stable amide bonds
Coupling chemistry that minimizes leakage of protein A ligand.

rmp Sepharose 4 Sepharose Fast Flow is composed of recombinant Protein A coupled to the well established Sepharose 4 Fast Flow base matrix by reductive amination resulting in multipoint attachment.

Reductive amination creates chemically stable amide bonds and resulting low ligand leakage. rmp Protein A Sepharose 4 Fast Flow is manufactured without using animal-derived components.

As member of the BioProcess resins range, rmp Sepharose 4 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support.

Parameter	rmp Protein A Sepharose Fast Flow
Chromatography technique	Antibody affinity chromatography
BioProcess resin	Yes
Ligand	Recombinant protein A (E.coli)
Particle size, d_50V¹	~90 µm
Matrix	cross-linked agarose, 4%, spherical
Ligand Coupling Method	Reductive Amination
Binding Capacity/ml Chromatography Medium：	>Min. 22 mg human IgG/mL
pH stability, operational²	3–10
pH stability, CIP³	3–12
Pressure/flow characteristics⁴	150–250 cm/h at <0.1 MPa in a XK 50/60 column with 5 cm diameter and 25 cm bed height (at 20°C using buffers with the same viscosity as water).
Storage	2 to 8°C, 20% Ethanol
Chemical stability	Stable in aqueous buffers commonly used in Protain A chromatography, 20% ethanol 20 mM, Sodium phosphate, 0.1 M Glycin/HCl pH 3.5, 0.1 M Glycin/HCl pH 2.5
Certificate of Analysis	Yes

¹Median particle size of the cumulative volume distribution.
²pH range where resin can be operated without significant change in function. pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at pH below 2.”
³pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function. pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at pH below 2.
⁴The pressure/flow characteristics describes the relationship between pressure and flow under the set circumstances. The pressure given shall not be taken as the maximum pressure of the resin. Pressure/flow test performed on the base matrix.

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 20 \| 欧洲Eur. ≥ 16 \| 東京Tokyo ≥ 5 \| 香港与北京 ≥ 20

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北实纵横化学试剂与生命科学产品解决方案

rmp蛋白A琼脂糖凝胶FF，rmp Protein A Sepharose Fast Flow

rmp Protein A Sepharose Fast Flow

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