过滤
关闭导航

(R)-(-)-布洛芬,(R)-(-)-Ibuprofen;98%

别名:(R)-布洛芬;(alphaR)-alpha-甲基-4-(2-甲基丙基)苯乙酸;(2R)-2-[4-(2-2-甲基丙基)苯基]丙酸;(R)-Ibuprofen;L-Ibuprofen;(alphaR)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid;R-(-)-p-Isobutylhydratropic acid;R-(-)-p-Isobutylhydratropic acid;(2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid

CAS编号: 51146-57-7;分子式: C13H18O2;分子量: 206.28;MDL号: MFCD00069290;PubChem编号: 114864
制造商品牌: BSZH
货号(SKU): L17780
CAS号: 51146-57-7
MDL号: MFCD00069290
技术支持 √ 增值税发票 √ 免费送货 √ 质量保障 √
¥576.00

基本描述

规格或纯度98%
英文名称(R)-(-)-Ibuprofen
别名(R)-布洛芬
英文别名(R)-Ibuprofen;L-Ibuprofen;(alphaR)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid; R-(-)-p-Isobutylhydratropic acid; R-(-)-p-Isobutylhydratropic acid;(2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid;
生化机理(R)-Ibuprofen, a nonsteroidal antiinflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2. Most of the activity resides in (S)-ibuprofen. It has been observed that the inversion of R(-)-ibuprofen to the S(+) antipode occurs in rat liver but not in either serosal or mucosal sides of the small intestine. (R)-Ibuprofen’s presence can be detected in urine throμgh mass chromatography. A liquid-chromatographic assay has been used to study the pharmacokinetics of the (S)- and (R)-Ibuprofen forms in plasma.
储存温度2-8°C储存
产品介绍

(R)-Ibuprofen是ibuprofen的低活性对映体。An inhibitor of Cox-1 and Cox-2.

产品介绍:

(R)-(-)-Ibuprofen 是 Ibuprofen 的 R 型异构体,对 COX 无作用,可以抑制 NF-κB 的活化;(R)-(-)-Ibuprofen 具有抗炎作用,可用于缓解疼痛的研究。

(R)-Ibuprofen, a nonsteroidal anti-inflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2.
An inhibitor of Cox-1 and Cox-2.

 

名称和标识符

IUPAC Name(2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid
INCHIInChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m1/s1
InChi KeyHEFNNWSXXWATRW-SNVBAGLBSA-N
Canonical SMILESCC(C)CC1=CC=C(C=C1)C(C)C(=O)O
分子式

C13H18O2

PubChem CID114864
分子量206.28

 

化学和物理性质

溶解性Soluble in methanol, 0.1 M NaOH, dichloromethane, and ethyl acetate.
密度1.03
沸点319.64 °C/760 mmHg
熔点50.5-52.5°C
折光率1.52
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10