Q琼脂糖凝胶HP，Q Sepharose High Performance

图片 Q琼脂糖凝胶HP，Q Sepharose High Performance
高性能Q琼脂糖凝胶是一种具有高分辨率的BioProcess强阴离子交换树脂，专为下游工艺中的高阶中间过程和精制步骤而设计。17101404；17101401；17101405；17-1014-04；17-1014-01；17-1014-05
制造商品牌: (安)法玛西亚 Amersham Pharmacia , 思拓凡 Cytiva
货号（SKU）: 17101401
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥4,290.00

Q Sepharose High Performance

Q Sepharose High Performance is a strong anion exchange BioProcess resin with high resolution designed for high intermediate and polishing steps in downstream processing。

高性能Q琼脂糖凝胶是一种具有高分辨率的BioProcess强阴离子交换树脂，专为下游工艺中的高阶中间过程和精制步骤而设计。

  • Strong anion exchanger for intermediate and final polishing steps
  • High resolution, high capacity separation with high recovery
  • High chemical stability for effective CIP/sanitization
  • BioProcess resin supported for industrial applications and well-established in approved processes
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.

Q Sepharose High Performance is composed of crosslinked agarose beads with a mean diameter of 34 µm, modified with quaternary (Q) strong anion exchange groups. It is designed for intermediate purification and polishing applications and to be used when resolution and capacity have priority. Q Sepharose High Performance has high chemical stability and withstands effective CIP/sanitization protocols using sodium hydroxide。

Q Sepharose High Performance is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Q Sepharose High Performance meets industrial demands with security of supply and comprehensive technical and regulatory support.

Q琼脂糖凝胶HP由平均直径为34 μm的交联琼脂糖微珠组成，并用季胺 （Q） 强阴离子交换基团修饰。它专为中度纯化和精纯应用而设计，可在分辨率和容量优先时使用。Q琼脂糖凝胶HP具有很高的化学稳定性，可承受使用氢氧化钠的有效CIP/消毒方案。

Q琼脂糖凝胶HP有多种不同的包装尺寸和方便的预装形式，便于放大和工艺开发。作为BioProcess填料系列的一员，Q琼脂糖凝胶HP通过供应链安全以及全面的技术和法规支持来满足工业需求。

 

参数Q Sepharose High Performance
BioProcess resinYes 
Charged Groups- N+(CH₃)₃ 
Chemical stability 1Stable in commonly used buffers: 8 M urea, 6 M guanidine HCl, 70% ethanol, 1 M NaOH, 1 M acetic acid, 30% isopropanol, 30% acetonitrile, 2% SDS 
Exclusion limit (Mr) (globular proteins)：~4 × 10⁶ 
Flow velocity30-150cm/h 
Ion Exchanger TypeStrong anion exchanger 
Ionic Capacity0.14-0.20 mmol Cl-/ml 
LigandQuaternary amine 
Ligand Coupling MethodEther linkages 
Matrix6% cross-linked agarose 
Particle Size24-44 µm 
Particle size, d50V 2~34 µm 
Pressure/Flow Specification150 cm/h (at < 3 bar, 25°C, 10 cm bed height) 
Storage4 to 30°C, 20% Ethanol 
pH stability, CIP 31–14 
pH stability, operational 42–12 
  • 11 M NaOH and acetic acid should be used only for cleaning purposes.
  • 2Median particle size of the cumulative volume distribution.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
  • 4pH range where resin can be operated without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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