Q琼脂糖凝胶 [高性能],Q Sepharose High Performance

高性能Q琼脂糖凝胶是一种具有高分辨率的强阴离子交换 BioProcess 树脂,专为下游加工中的高中间和精制步骤而设计。17101404;17101401;17101405
货号(SKU): 17101403
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Q Sepharose High Performance is a strong anion exchange BioProcess resin with high resolution designed for high intermediate and polishing steps in downstream processing。

用于有效 CIP/消毒的高化学稳定性
BioProcess 树脂支持工业应用,并在批准的工艺中建立良好
Q Sepharose High Performance 由平均直径为 34 µm 的交联琼脂糖珠组成,并用四元 (Q) 强阴离子交换基团修饰。它专为中间纯化和精制应用而设计,并在分辨率和容量优先时使用。 Q Sepharose High Performance 具有高化学稳定性,并能承受使用氢氧化钠的有效 CIP/消毒方案

Q Sepharose High Performance 提供一系列不同的散装尺寸和方便的预包装形式,便于放大和工艺开发。作为 BioProcess 树脂系列的一员,Q Sepharose High Performance 凭借供应安全性以及全面的技术和法规支持满足工业需求。


  • Strong anion exchanger for intermediate and final polishing steps
  • High resolution, high capacity separation with high recovery
  • High chemical stability for effective CIP/sanitization
  • BioProcess resin supported for industrial applications and well-established in approved processes
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.

Q Sepharose High Performance is composed of crosslinked agarose beads with a mean diameter of 34 µm, modified with quaternary (Q) strong anion exchange groups. It is designed for intermediate purification and polishing applications and to be used when resolution and capacity have priority. Q Sepharose High Performance has high chemical stability and withstands effective CIP/sanitization protocols using sodium hydroxide

Q Sepharose High Performance is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Q Sepharose High Performance meets industrial demands with security of supply and comprehensive technical and regulatory support.


ParameterQ Sepharose High Performance, 1 L
BioProcess resinYes 
LigandQuaternary amine 
Particle size, d50V1~34 µm 
Ion Exchanger TypeStrong anion exchanger 
Matrix6% cross-linked agarose 
Particle Size24-44 µm 
Ligand Coupling MethodEther linkages 
Ionic Capacity0.14-0.20 mmol Cl-/ml 
pH stability, operational22–12 
pH stability, CIP31–14 
Flow rate> 1.0 ml/min 
Pressure/Flow Specification150 cm/h (at < 3 bar, 25°C, 10 cm bed height) 
Flow velocity30-150cm/h 
Exclusion limit (Mr) (globular proteins)~4 × 10⁶ 
Storage4 to 30°C, 20% Ethanol 
Chemical stability4Stable in commonly used buffers: 8 M urea, 6 M guanidine HCl, 70% ethanol, 1 M NaOH, 1 M acetic acid, 30% isopropanol, 30% acetonitrile, 2% SDS  
Charged Groups- N+(CH₃)₃ 
Certificate of AnalysisYes 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
  • 41 M NaOH and acetic acid should be used only for cleaning purposes.
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16