PH-797804，≥98% (HPLC)

图片 PH-797804，≥98% (HPLC)
别名：PH797804；3-Bromo-4-(2,4-difluorobenzyl)oxy-1-5-(methylamino)carbonyl-2-methylphenyl-6-methylpyridin-2(1H)-one, 3-3-Bromo-4-(2,4-difluorophenyl)methoxy-6-methyl-2-oxo-1(2H)-pyridinyl-N,4-dimethyl-benzamide, PH 797804

Empirical Formula (Hill Notation): C22H19BrF2N2O3 CAS号: 586379-66-0 分子量: 477.30 MDL编号: MFCD18251426 PubChem化学物质编号: 329823795
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0259
CAS号: 586379-66-0
MDL号: MFCD18251426
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说明

生化/生理作用

PH-797804 is an orally active, potent and readily reversible ATP competitive inhibitor of the alpha isoform of human p38 MAP kinase. PH-797804 blocks inflammation-induced production of cytokines and proinflammatory mediators.
 

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

manufacturer/tradename

Pfizer®

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear

创始人

Pfizer

储存温度

20-25°C

SMILES string

CC1=CC(OCC2=C(F)C=C(F)C=C2)=C(Br)C(N1C3=CC(C(NC)=O)=CC=C3C)=O

InChI

1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)

InChI key

KCAJXIDMCNPGHZ-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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