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PF-956980 hydrate,≥98% (HPLC)

别名:PF956980水合物;{(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-pyrrolidin-1-yl-methanone hydrate

Empirical Formula (Hill Notation): C18H26N6O · xH2O 分子量: 342.44 (anhydrous basis) MDL编号: MFCD18452852 PubChem化学物质编号: 329823736 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0151
CAS号: 1262832-74-5
MDL号: MFCD18452852
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$421.11

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-956980 is a FGF1 receptor antagonist; PDGF receptor modulator; Flt3 tyrosine kinase modulator; and VEGF antagonist.
PF-956980 是一种 FGF1 受体拮抗剂; PDGF 受体调节剂; Flt3 酪氨酸激酶调节剂; 和 VEGF 拮抗剂。
 

特点和优势

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.
This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

旋光性

[α]/D +33 to +40°, c = 0.5 in methanol

mfr. no.

Pfizer®

颜色

white to off-white

溶解性

DMSO: ≥50 mg/mL

创始人

Pfizer

储存温度

2-8°C

SMILES string

O.C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)N4CCCC4

InChI

1S/C18H26N6O.H2O/c1-13-6-10-24(18(25)23-8-3-4-9-23)11-15(13)22(2)17-14-5-7-19-16(14)20-12-21-17;/h5,7,12-13,15H,3-4,6,8-11H2,1-2H3,(H,19,20,21);1H2/t13-,15+;/m1./s1

InChI key

VZUKSTKLTSSYKP-PBCQUBLHSA-N

 

安全信息

象形图

Skull and crossbones

警示用语:

Danger

危险声明

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16