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PF-4778574,≥98% (HPLC)

别名:N-{(3R,4S)-3-4-(5-Cyano-2-thienyl)phenyltetrahydro-2H-pyran-4-yl}propane-2-sulfonamide, N-(3R,4S)-3-4-(5-Cyano-2-thienyl)phenyltetrahydro-2H-pyran-4-yl-2-propanesulfonamide

Empirical Formula (Hill Notation): C19H22N2O3S2 CAS号: 1219633-99-4 分子量: 390.52 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0211
CAS号: 1219633-99-4
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$356.92

说明

PF-4778574 可用作大鼠皮层神经元中 α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) 的增强剂。
PF-4778574 是一种有效的 AMPA 受体正变构调节剂 (PAM),已被证明可增强动物模型的认知能力。

应用

PF-4778574 may be used as a potentiator of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) in rat cortical neurons.
 

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models.
 

特点和优势

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

危害代码

T

风险声明

25

安全声明

45

RIDADR

NONH for all modes of transport

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16