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PF-06281355 [PF-1355],≥98% (HPLC)

别名:PF06281355;6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide, PF 6281355

Empirical Formula (Hill Notation): C14H15N3O4S CAS号: 1435467-38-1 分子量: 321.35 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0277
CAS号: 1435467-38-1
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$233.74

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-06281355 (PF-1355) is an orally available, selective and potent mechanism based inhibitor of the myeloperoxidase (MPO) that reduces plasma MPO activity, vascular edema, neutrophil recruitment, and elevated circulating cytokines. PF-06281355 suppresses albuminuria and chronic renal dysfunction in model of anti-Glomerular Basement Membrane (GBM) disease.
 
PF-06281355 (PF-1355) 是一种可口服、选择性和有效机制的髓过氧化物酶 (MPO) 抑制剂,可降低血浆 MPO 活性、血管水肿、中性粒细胞募集和循环细胞因子升高。 PF-06281355 在抗肾小球基底膜 (GBM) 疾病模型中抑制白蛋白尿和慢性肾功能障碍。
 

其他说明

This compound was developed by Pfizer for Nitric Oxide & Cell Stress research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

RIDADR

NONH for all modes of transport

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16