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PF-05190457,≥95% (HPLC)

别名:2-(2-Methylimidazo2,1-b1,3thiazol-6-yl)-1-{2-(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl-2,7-diazaspiro3.5non-7-ylethanone, PF 5190457, 1-2-(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl-2,7-diazaspiro3.5non-7-yl-2-(2-methylimidazo2,1-bthiazol-6-yl)-ethanone, PF-5190457

Empirical Formula (Hill Notation): C29H32N6OS CAS号: 1334782-79-4 分子量: 512.67 MDL编号: MFCD28411390 PubChem化学物质编号: 329823804
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0270
CAS号: 1334782-79-4
MDL号: MFCD28411390
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$354.21

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
PF-05190457 是一种口服有效的选择性生长素释放肽受体反向激动剂。 PF-05190457 有效增加葡萄糖刺激的人胰岛中的胰岛素分泌。
 

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥95% (HPLC)

形式

powder

旋光性

α/D +45 to +55°, c = 0.5 in methanol

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

创始人

Pfizer

储存温度

room temp

SMILES string

CC1=CN2C(S1)=NC(CC(N3CCC4(CN(C@H(CCC5=C6)C5=CC=C6C7=NC=NC(C)=C7)C4)CC3)=O)=C2

InChI

1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1

InChI key

ZIUDADZJCKGWKR-AREMUKBSSA-N

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16