PF-05190457，≥95% (HPLC)

图片 PF-05190457，≥95% (HPLC)
别名：1-[2-[(1R)-2,3-二氢-5-(6-甲基-4-嘧啶基)-1H-茚-1-基]-2,7-二氮杂螺[3.5]非-7-基]-2-(2-甲基咪唑并[2,1-b]噻唑-6-基)乙酮；2-（2-甲基咪唑并[2，1-b][1，3]噻唑-6-基）-1-{2-[（1R）-5-（6-甲基嘧啶-4-基）-2，3-二氢-1H-茚-1-基]-2，7-二氮杂螺[3.5]非-7-基列酮；2-(2-Methylimidazo2,1-b1,3thiazol-6-yl)-1-{2-(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl-2,7-diazaspiro3.5non-7-ylethanone, PF 5190457, 1-2-(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl-2,7-diazaspiro3.5non-7-yl-2-(2-methylimidazo2,1-bthiazol-6-yl)-ethanone, PF-5190457

Empirical Formula (Hill Notation): C29H32N6OS CAS号: 1334782-79-4 分子量: 512.67 MDL编号: MFCD28411390 PubChem化学物质编号: 329823804
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0270
CAS号: 1334782-79-4
MDL号: MFCD28411390
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说明

生化/生理作用

PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
 

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥95% (HPLC)

形式

powder

旋光性

α/D +45 to +55°, c = 0.5 in methanol

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

创始人

Pfizer

储存温度

room temp

SMILES string

CC1=CN2C(S1)=NC(CC(N3CCC4(CN(C@H(CCC5=C6)C5=CC=C6C7=NC=NC(C)=C7)C4)CC3)=O)=C2

InChI

1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1

InChI key

ZIUDADZJCKGWKR-AREMUKBSSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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