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PF-04418948,≥98% (HPLC)

别名:1-(4-氟苯甲酰基)-3-(6-甲氧基-2-萘基)氧甲基-3-氮杂环丁烷羧酸;1-(4-Fluorobenzoyl)-3-(6-methoxy-2-naphthalenyl)oxymethyl-3-azetidinecarboxylic acid

Empirical Formula (Hill Notation): C23H20FNO5 CAS号: 1078166-57-0 分子量: 409.41 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0213
CAS号: 1078166-57-0
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$234.28

说明

应用

PF-04418948 has been used in TG (trigeminal ganglion) explant culture.
 

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-04418948 is a PGE2 Receptor (EP2) specific antagonist (IC50 = 16 nM) with greater than 2000-fold selectivity over other EP subtypes. PF-04418948 inhibits EP2 activity in smooth muscle preps from human, dog and mouse.
PF-04418948 represses the formation of colorectal tumor.
 

特点和优势

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
 

其他说明

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16