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PF-03246799 hydrochloride,≥98% (HPLC)

别名:PF03246799盐酸盐;PF-3246799 hydrochloride, 6,7,8,9-Tetrahydro-2-(phenylmethyl)-5H-pyrimido[4,5-d]azepine hydrochloride

Empirical Formula (Hill Notation): C15H17N3 · xHCl CAS号: 1065114-52-4 分子量: 239.32 (free base basis) PubChem化学物质编号: 329823781 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0229
CAS号: 1065114-52-4
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$354.21

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

PF-3246799 is a potent serotonin 5-HT2C receptor agonist with an EC50 of 4.5 nM and minimal activity at 5-HT2A and 5-HT2B receptors. PF-3246799 had good efficacy in a preclinical canine model of stress urinary incontinence.
 
PF-3246799 是一种有效的 5-羟色胺 5-HT2C 受体激动剂,EC50 为 4.5 nM,对 5-HT2A 和 5-HT2B 受体的活性最低。 PF-3246799 在犬压力性尿失禁的临床前模型中具有良好的疗效。
 

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

H2O: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

SMILES string

C1(CC2=NC(CCNCC3)=C3C=N2)=CC=CC=C1.Cl

InChI

1S/C15H17N3.ClH/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15;/h1-5,11,16H,6-10H2;1H

InChI key

ICVPRIZGSIUCOE-UHFFFAOYSA-N

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16