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PF-01247324,≥98% (HPLC)

别名:PF01247324;N-Methyl-6-amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide, 6-Amino-N-methyl-5-(2,3,5-trichlorophenyl)-2-Pyridinecarboxamide, 6-Amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxylic acid methylamide, PF-1247324, PF 01247324

Empirical Formula (Hill Notation): C13H10Cl3N3O CAS号: 875051-72-2 分子量: 330.60 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0274
CAS号: 875051-72-2
MDL号: MFCD28156579
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$233.74

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

In humans, PF-01247324 [6-amino-5-(2, 3, 5-trichloro-phenyl)-pyridine-2-carboxylic acid methylamide] prevents native tetrodotoxin-resistant (TTX-R) currents in dorsal root ganglion (DRG) neurons.
PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.
 
在人类中,PF-01247324 [6-氨基-5-(2, 3, 5-三氯-苯基)-吡啶-2-羧酸甲酰胺] 可防止背根神经节 (DRG) 中的天然河豚毒素抗性 (TTX-R) 电流 ) 神经元。
PF-01247324 是一种口服生物可利用、选择性和有效的 NaV1.8 通道阻滞剂,可抑制在啮齿动物疼痛行为模型中表现出镇痛功效。
 

其他说明

This compound was developed by Pfizer for Ion Channel research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Skull and crossbones

警示用语:

Danger

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16