PD153035盐酸盐，PD153035 hydrochloride；≥98% (HPLC)

图片 PD153035盐酸盐，PD153035 hydrochloride；≥98% (HPLC)
别名：SU-5271；4-[（3-溴苯基）氨基]-6,7-二甲氧基喹唑啉盐酸盐；4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride, AG 1517, PD 153035, SU 5271, ZM 252868

Empirical Formula (Hill Notation): C16H14BrN3O2 · HCl CAS号: 183322-45-4 分子量: 396.67 MDL编号: MFCD01074805 PubChem化学物质编号: 329825555 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0564
CAS号: 183322-45-4
MDL号: MFCD01074805
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说明

生化/生理作用

PD153035 is apotent and selective ATP competitive inhibitor of the epidermal growth factor receptor tyrosine kinase EGFR.
 

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES string

Cl.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC

InChI

1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H

InChI key

ZJOKWAWPAPMNIM-UHFFFAOYSA-N

 

安全信息

象形图

CorrosionSkull and crossbones
GHS05,GHS06

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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