PD-180970，≥98% (HPLC)

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别名：6-(2,6-Dichlorophenyl)-2-(4-fluoro-3-methylphenyl)amino-8-methyl-pyrido2,3-dpyrimidin-7(8H)-one, PF-1515965

Empirical Formula (Hill Notation): C21H15Cl2FN4O CAS号: 287204-45-9 分子量: 429.27 MDL编号: MFCD10565929 PubChem化学物质编号: 329823727 NACRES: NA.77

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: PZ0142

CAS号: 287204-45-9

MDL号: MFCD10565929

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目录价.SKU-Variant

5mg
25mg [+$910.01]

$421.11

数量:

说明

包装

5, 25 mg in glass bottle

生化/生理作用

PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase.

PD-180970 是 p210 Bcr-Abl 酪氨酸激酶的有效抑制剂。

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC^®¹²⁸⁰), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC^®^Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Pfizer is a registered trademark of Pfizer, Inc.

属性

测定

≥98% (HPLC)

mfr. no.

Pfizer^®

颜色

yellow

溶解性

DMSO: >20 mg/mL

创始人

Pfizer

储存温度

2-8°C

SMILES string

CN1C(=O)C(=Cc2cnc(Nc3ccc(F)c(C)c3)nc12)c4c(Cl)cccc4Cl

InChI

1S/C21H15Cl2FN4O/c1-11-8-13(6-7-17(11)24)26-21-25-10-12-9-14(20(29)28(2)19(12)27-21)18-15(22)4-3-5-16(18)23/h3-10H,1-2H3,(H,25,26,27)

InChI key

SLCFEJAMCRLYRG-UHFFFAOYSA-N

安全信息

象形图

GHS06

警示用语：

Danger

危险声明

H301 - H413

预防措施声明

P273 - P301 + P310 + P330

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 33 \| 欧洲Eur. ≥ 27 \| 東京Tokyo ≥ 9 \| 香港与北京 ≥ 16