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N-(4-溴苯基)-N-苯基丙烯酰胺;N-(4-Bromophenyl)-N-phenylacrylamide;≥95%

别名:Electrophilic scout fragment, KB05, Scout fragment for targetable cysteine; Empirical Formula (Hill Notation): C15H12BrNO CAS号: 1956368-15-2 分子量: 302.17
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 911798
CAS号: 1956368-15-2
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥3,620.61

说明

应用

N-(4-Bromophenyl)-N-phenylacrylamide is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins. This fragment electrophile, or ″scout″ fragment, can be used alone in fragment-based covalent ligand discovery or incorporated into bifunctional tools such as electrophilic PROTAC® molecules for targeted protein degradation as demonstrated by the Cravatt Lab for E3 ligase discovery.
 

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
 
 

属性

质量水平

检测方案

≥95%

形式

(Powder or crystals or solid or chunks)

储存温度

2-8°C

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 10 | 欧洲Eur. ≥ 8 | 東京Tokyo ≥ 6 | 香港与北京 ≥ 60